8-Thia-1,6-diazabicyclo[4.3.0]nonane-7,9-dione

8-Thia-1,6-diaza­bicyclo­[4.3.0]nonane-7,9-dione

There are two independent mol-ecules, A and B, in the asymmetric unit of the title compound, C(6)H(8)N(2)O(2)S. In the crystal, pairs of inter-molecular S⋯O contacts [3.286 (1) Å] link the B mol-ecules into inversion dimers.

6,7-Diphenyl-5-thia-7-aza­spiro­[2.6]nonan-8-one

The asymmetric unit of the title compound, C19H19NOS, contains two independent mol-ecules (A and B), in both of which the 1,3-thia-zepan-4-one ring adopts a chair-type conformation. The dihedral angles between the two phenyl rings are 65.28 (8) and 60.31 (9)° for mol-ecules A and B, respectively. In the crystal, mol-ecules are linked by weak C-H⋯O inter-actions, resulting in a three-dimensional...

Analytical Chemistry: Vol.79, Issue 16 (ACS Publications)

8-Phenyl-10-oxa-8-aza­tricyclo­[4.3.0.12,5]decane-7,9-dione

The reaction of aniline with norcantharidin produced the imide title compound, C(14)H(13)NO(3), which shows no significant hydrogen bonds in the crystal structure. The dihedral angle between the phenyl and pyrrolidine rings is 48.48 (6)°.

Hotakainen 16/8

Tumor-associated trypsin inhibitor (TATI) is a marker of mucinous ovarian carcinoma, but it is also widely expressed in other malignant tumors and normal human tissues. Elevated serum concentrations of TATI are of prognostic value in ovarian, kidney, and bladder cancer. Tumor-associated trypsin is co-expressed with TATI in many malignancies and is thought to be involved in tumor invasion. TATI ...